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Myeloid differentiation factor 88 signaling in donor T cells accelerates graft-versus-host disease
Myeloid differentiation factor 88 (MyD88) signaling has a crucial role in activation of both innate and adoptive immunity. MyD88 transduces signals via Toll-like receptor and interleukin-1 receptor superfamily to the NFκB pathway and inflammasome by forming a molecular complex with interleukin-1 rec...
Autores principales: | Matsuoka, Satomi, Hashimoto, Daigo, Kadowaki, Masanori, Ohigashi, Hiroyuki, Hayase, Eiko, Yokoyama, Emi, Hasegawa, Yuta, Tateno, Takahiro, Chen, Xuanzhong, Aoyama, Kazutoshi, Oka, Hideyo, Onozawa, Masahiro, Takeda, Kiyoshi, Akashi, Koichi, Teshima, Takanori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939524/ https://www.ncbi.nlm.nih.gov/pubmed/31048358 http://dx.doi.org/10.3324/haematol.2018.203380 |
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