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Ablation of Hmgb1 in Intestinal Epithelial Cells Causes Intestinal Lipid Accumulation and Reduces NASH in Mice

Nonalcoholic steatohepatitis (NASH) is a metabolic disorder in which poor nutrition and the gut‐to‐liver interaction play a major role. We previously established that hepatic high mobility group box‐1 (HMGB1) is involved in chronic liver disease. HMGB1 increases in patients with NASH and it is expre...

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Detalles Bibliográficos
Autores principales: Gaskell, Harriet, Ge, Xiaodong, Desert, Romain, Das, Sukanta, Han, Hui, Lantvit, Daniel, Guzman, Grace, Nieto, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939545/
https://www.ncbi.nlm.nih.gov/pubmed/31909358
http://dx.doi.org/10.1002/hep4.1448