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Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors

In vitro gametogenesis is the process of making germline cells from human pluripotent stem cells. The foundation of this model is the quality of the first progenitors called primordial germ cells (PGCs), which in vivo are specified during the peri-implantation window of human development. Here, we s...

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Detalles Bibliográficos
Autores principales: Chen, Di, Sun, Na, Hou, Lei, Kim, Rachel, Faith, Jared, Aslanyan, Marianna, Tao, Yu, Zheng, Yi, Fu, Jianping, Liu, Wanlu, Kellis, Manolis, Clark, Amander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939677/
https://www.ncbi.nlm.nih.gov/pubmed/31875561
http://dx.doi.org/10.1016/j.celrep.2019.11.083