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Lodoxamide Attenuates Hepatic Fibrosis in Mice: Involvement of GPR35

A previous pharmacogenomic analysis identified cromolyn, an anti-allergic drug, as an effective anti-fibrotic agent that acts on hepatocytes and stellate cells. Furthermore, cromolyn was shown to be a G protein-coupled receptor 35 (GPR35) agonist. However, it has not been studied whether anti-fibrot...

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Detalles Bibliográficos
Autores principales: Kim, Mi-Jeong, Park, Soo-Jin, Nam, So-Yeon, Im, Dong-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939691/
https://www.ncbi.nlm.nih.gov/pubmed/31189299
http://dx.doi.org/10.4062/biomolther.2018.227