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Inhibitory Effect of Probenecid on Osteoclast Formation via JNK, ROS and COX-2

Probenecid is a representative drug used in the treatment of gout. A recent study showed that probenecid effectively inhibits oxidative stress in neural cells. In the present study, we investigated whether probenecid can affect osteoclast formation through the inhibition of reactive oxygen species (...

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Detalles Bibliográficos
Autores principales: Cheng, Mi Hyun, Kim, Sung-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939694/
https://www.ncbi.nlm.nih.gov/pubmed/31474032
http://dx.doi.org/10.4062/biomolther.2019.047