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Four Novel Synthetic Tryptamine Analogs Induce Head-Twitch Responses and Increase 5-HTR2a in the Prefrontal Cortex in Mice

Tryptamines are monoamine alkaloids with hallucinogenic properties and are widely abused worldwide. To hasten the regulations of novel substances and predict their abuse potential, we designed and synthesized four novel synthetic tryptamine analogs: Pyrrolidino tryptamine hydrochloride (PYT HCl), Pi...

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Detalles Bibliográficos
Autores principales: Abiero, Arvie, Ryu, In Soo, Botanas, Chrislean Jun, Custodio, Raly James Perez, Sayson, Leandro Val, Kim, Mikyung, Lee, Hyun Jun, Kim, Hee Jin, Seo, Joung-Wook, Cho, Min Chang, Lee, Kun Won, Yoo, Sung Yeun, Jang, Choon-Gon, Lee, Yong Sup, Cheong, Jae Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939696/
https://www.ncbi.nlm.nih.gov/pubmed/31230432
http://dx.doi.org/10.4062/biomolther.2019.049