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Generation of a genetically modified human embryonic stem cells expressing fluorescence tagged ATOX1

ATOX1 is a copper chaperone involved in intracellular copper homeostasis, cell proliferation, and tumor progression. To investigate the physiologically relevant molecular mechanism of ATOX1 by using imaging-based approaches, we genetically modified ATOX1 in H1 hESCs to express mCherry-ATOX1 fusion p...

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Detalles Bibliográficos
Autores principales: Wen, Meng-Hsuan, Xie, Xihong, Tu, Jian, Lee, Dung-Fang, Chen, Tai-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939864/
https://www.ncbi.nlm.nih.gov/pubmed/31704540
http://dx.doi.org/10.1016/j.scr.2019.101631