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Temporal Control of the TGF-β Signaling Network by Mouse ESC MicroRNA Targets of Different Affinities
Although microRNAs (miRNAs) function in the control of embryonic stem cell (ESC) pluripotency, a systems-level understanding is still being developed. Through the analysis of progressive Argonaute (Ago)-miRNA depletion and rescue, including stable Ago knockout mouse ESCs, we uncover transforming gro...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939994/ https://www.ncbi.nlm.nih.gov/pubmed/31775039 http://dx.doi.org/10.1016/j.celrep.2019.10.109 |