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Temporal Control of the TGF-β Signaling Network by Mouse ESC MicroRNA Targets of Different Affinities

Although microRNAs (miRNAs) function in the control of embryonic stem cell (ESC) pluripotency, a systems-level understanding is still being developed. Through the analysis of progressive Argonaute (Ago)-miRNA depletion and rescue, including stable Ago knockout mouse ESCs, we uncover transforming gro...

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Detalles Bibliográficos
Autores principales: Kelly, Timothy J., Brümmer, Anneke, Hooshdaran, Nima, Tariveranmoshabad, Mito, Zamudio, Jesse R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939994/
https://www.ncbi.nlm.nih.gov/pubmed/31775039
http://dx.doi.org/10.1016/j.celrep.2019.10.109