Exchange of water for sterol underlies sterol egress from a StARkin domain

Previously we identified Lam/GramD1 proteins, a family of endoplasmic reticulum membrane proteins with sterol-binding StARkin domains that are implicated in intracellular sterol homeostasis. Here, we show how these proteins exchange sterol molecules with membranes. An aperture at one end of the StAR...

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Detalles Bibliográficos
Autores principales: Khelashvili, George, Chauhan, Neha, Pandey, Kalpana, Eliezer, David, Menon, Anant K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940019/
https://www.ncbi.nlm.nih.gov/pubmed/31799930
http://dx.doi.org/10.7554/eLife.53444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940019/
https://www.ncbi.nlm.nih.gov/pubmed/31799930
http://dx.doi.org/10.7554/eLife.53444

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