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Upregulation of cortical GABA(A) receptor concentration in fibromyalgia

An imbalance between excitatory and inhibitory neurotransmission has been linked to fibromyalgia (FM). Magnetic resonance spectroscopy has shown increased levels of glutamate in the insula and posterior cingulate cortex in FM as well as reduced insular levels of gamma-aminobutyric acid (GABA). Both...

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Detalles Bibliográficos
Autores principales: Pomares, Florence B., Roy, Steve, Funck, Thomas, Feier, Natasha A., Thiel, Alexander, Fitzcharles, Mary-Ann, Schweinhardt, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940028/
https://www.ncbi.nlm.nih.gov/pubmed/31569142
http://dx.doi.org/10.1097/j.pain.0000000000001707