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Phospholipid prodrug conjugates of insoluble chemotherapeutic agents for ultrasound targeted drug delivery
The hydrophobicity and high potency of many therapeutic agents makes them difficult to use effectively in clinical practice. This work focuses on conjugating phospholipid tails (2T) onto podophyllotoxin (P) and its analogue (N) using a linker and characterizing the effects of their incorporation int...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Ivyspring International Publisher
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940203/ https://www.ncbi.nlm.nih.gov/pubmed/31911893 http://dx.doi.org/10.7150/ntno.37738 |