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Sertoli cell ablation and replacement of the spermatogonial niche in mouse

Spermatogonia, which produce sperm throughout the male lifetime, are regulated inside a niche composed of Sertoli cells, and other testis cell types. Defects in Sertoli cells often lead to infertility, but replacement of defective cells has been limited by the inability to deplete the existing popul...

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Detalles Bibliográficos
Autores principales: Yokonishi, Tetsuhiro, McKey, Jennifer, Ide, Shintaro, Capel, Blanche
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940386/
https://www.ncbi.nlm.nih.gov/pubmed/31896751
http://dx.doi.org/10.1038/s41467-019-13879-8