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B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids

Short-chain fatty acids (SCFAs) butyrate and propionate are metabolites from dietary fiber's fermentation by gut microbiota that can affect differentiation or functions of T cells, macrophages and dendritic cells. We show here that at low doses these SCFAs directly impact B cell intrinsic funct...

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Detalles Bibliográficos
Autores principales: Sanchez, Helia N., Moroney, Justin B., Gan, Huoqun, Shen, Tian, Im, John L., Li, Tianbao, Taylor, Julia R., Zan, Hong, Casali, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940392/
https://www.ncbi.nlm.nih.gov/pubmed/31896754
http://dx.doi.org/10.1038/s41467-019-13603-6