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Decreased inward rectifier and voltage-gated K(+) currents of the right septal coronary artery smooth muscle cells in pulmonary arterial hypertensive rats

In vascular smooth muscle, K(+) channels, such as voltage-gated K(+) channels (Kv), inward-rectifier K(+) channels (Kir), and big-conductance Ca(2+)-activated K(+) channels (BK(Ca)), establish a hyperpolarized membrane potential and counterbalance the depolarizing vasoactive stimuli. Additionally, K...

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Detalles Bibliográficos
Autores principales: Kim, Sung Eun, Yin, Ming Zhe, Kim, Hae Jin, Vorn, Rany, Yoo, Hae Young, Kim, Sung Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940494/
https://www.ncbi.nlm.nih.gov/pubmed/31908580
http://dx.doi.org/10.4196/kjpp.2020.24.1.111