Fundc1-dependent mitophagy is obligatory to ischemic preconditioning-conferred renoprotection in ischemic AKI via suppression of Drp1-mediated mitochondrial fission

FUN14 domain-containing protein 1 (Fundc1)-dependent mitophagy, mainly activated by ischemic/hypoxic preconditioning, benefits acute myocardial reperfusion injury and chronic metabolic syndrome via sustaining mitochondrial homeostasis. Mitochondrial fission plays a pathogenic role in ischemic acute...

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Detalles Bibliográficos
Autores principales: Wang, Jin, Zhu, Pingjun, Li, Ruibing, Ren, Jun, Zhou, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940662/
https://www.ncbi.nlm.nih.gov/pubmed/31901590
http://dx.doi.org/10.1016/j.redox.2019.101415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940662/
https://www.ncbi.nlm.nih.gov/pubmed/31901590
http://dx.doi.org/10.1016/j.redox.2019.101415

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