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Humanized Mice as an Effective Evaluation System for Peptide Vaccines and Immune Checkpoint Inhibitors

Peptide vaccination was developed for the prevention and therapy of acute and chronic infectious diseases and cancer. However, vaccine development is challenging, because the patient immune system requires the appropriate human leukocyte antigen (HLA) recognition with the peptide. Moreover, antigens...

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Detalles Bibliográficos
Autores principales: Kametani, Yoshie, Ohno, Yusuke, Ohshima, Shino, Tsuda, Banri, Yasuda, Atsushi, Seki, Toshiro, Ito, Ryoji, Tokuda, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940818/
https://www.ncbi.nlm.nih.gov/pubmed/31888191
http://dx.doi.org/10.3390/ijms20246337