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Optimized Xenograft Protocol for Chronic Lymphocytic Leukemia Results in High Engraftment Efficiency for All CLL Subgroups

Preclinical drug development for human chronic lymphocytic leukemia (CLL) requires robust xenograft models recapitulating the entire spectrum of the disease, including all prognostic subgroups. Current CLL xenograft models are hampered by inefficient engraftment of good prognostic CLLs, overgrowth w...

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Detalles Bibliográficos
Autores principales: Decker, Sarah, Zwick, Anabel, Khaja Saleem, Shifa, Kissel, Sandra, Rettig, Andres, Aumann, Konrad, Dierks, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940872/
https://www.ncbi.nlm.nih.gov/pubmed/31842407
http://dx.doi.org/10.3390/ijms20246277