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Less Cytotoxic Protoflavones as Antiviral Agents: Protoapigenone 1′-O-isopropyl ether Shows Improved Selectivity Against the Epstein–Barr Virus Lytic Cycle

Protoflavones, a rare group of natural flavonoids with a non-aromatic B-ring, are best known for their antitumor properties. The protoflavone B-ring is a versatile moiety that might be explored for various pharmacological purposes, but the common cytotoxicity of these compounds is a limitation to su...

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Detalles Bibliográficos
Autores principales: Vágvölgyi, Máté, Girst, Gábor, Kúsz, Norbert, Ötvös, Sándor B., Fülöp, Ferenc, Hohmann, Judit, Servais, Jean-Yves, Seguin-Devaux, Carole, Chang, Fang-Rong, Chen, Michael S., Chang, Li-Kwan, Hunyadi, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940897/
https://www.ncbi.nlm.nih.gov/pubmed/31842358
http://dx.doi.org/10.3390/ijms20246269