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SYK Targeting Represents a Potential Therapeutic Option for Relapsed Resistant Pediatric ETV6-RUNX1 B-Acute Lymphoblastic Leukemia Patients

The presence of the chromosomal rearrangement t(12;21)(ETV6-RUNX1) in childhood B-acute lymphoblastic leukemia (B-ALL) is an independent predictor of favorable prognosis, however relapses still occur many years later after stopping therapy, and patients often display resistance to current treatments...

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Detalles Bibliográficos
Autores principales: Serafin, Valentina, Porcù, Elena, Cortese, Giuliana, Mariotto, Elena, Veltri, Giulia, Bresolin, Silvia, Basso, Giuseppe, Accordi, Benedetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940898/
https://www.ncbi.nlm.nih.gov/pubmed/31817853
http://dx.doi.org/10.3390/ijms20246175