Pharmacological Inhibition of TFF3 Enhances Sensitivity of CMS4 Colorectal Carcinoma to 5-Fluorouracil through Inhibition of p44/42 MAPK

Increased expression of trefoil factor 3 (TFF3) has been reported in colorectal carcinoma (CRC), being correlated with distant metastasis and poor clinical outcomes. Amongst the CRC subtypes, mesenchymal (CMS4) CRC is associated with the worst survival outcome. Herein, the functional roles of TFF3 a...

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Detalles Bibliográficos
Autores principales: Chen, Ru-Mei, Chiou, Yi-Shiou, Chong, Qing-Yun, Poh, Han-Ming, Tan, Tuan-Zea, Zhang, Meng-Yi, Ma, Lan, Zhu, Tao, Pandey, Vijay, Basappa, Kumar, Alan Prem, Lobie, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940926/
https://www.ncbi.nlm.nih.gov/pubmed/31835445
http://dx.doi.org/10.3390/ijms20246215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940926/
https://www.ncbi.nlm.nih.gov/pubmed/31835445
http://dx.doi.org/10.3390/ijms20246215

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