Development of Thiazolidinedione-Based HDAC6 Inhibitors to Overcome Methamphetamine Addiction

Thiazolidinedione is a five-membered heterocycle that is widely used in drug discovery endeavors. In this study, we report the design, synthesis, and biological evaluation of a series of thiazolidinedione-based HDAC6 inhibitors. In particular, compound 6b exerts an excellent inhibitory activity agai...

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Detalles Bibliográficos
Autores principales: Sharma, Chiranjeev, Oh, Yong Jin, Park, Byoungduck, Lee, Sooyeun, Jeong, Chul-Ho, Lee, Sangkil, Seo, Ji Hae, Seo, Young Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940941/
https://www.ncbi.nlm.nih.gov/pubmed/31835389
http://dx.doi.org/10.3390/ijms20246213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940941/
https://www.ncbi.nlm.nih.gov/pubmed/31835389
http://dx.doi.org/10.3390/ijms20246213

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