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Aldh2 Attenuates Stem Cell Factor/Kit-Dependent Signaling and Activation in Mast Cells

Mitochondrial aldehyde dehydrogenase (ALDH2) metabolizes endogenous and exogenous aldehydes and protects cells against oxidative injury. Inactivating genetic polymorphisms in humans are common and associate with alcohol flush reactions. However, whether mast cell Aldh2 activity impacts normal mast c...

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Detalles Bibliográficos
Autores principales: Kim, Do-Kyun, Cho, Young-Eun, Song, Byoung-Joon, Kawamoto, Toshihiro, Metcalfe, Dean D., Olivera, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940998/
https://www.ncbi.nlm.nih.gov/pubmed/31835486
http://dx.doi.org/10.3390/ijms20246216