Biallelic Deletion of Pxdn in Mice Leads to Anophthalmia and Severe Eye Malformation

Peroxidasin (PXDN) is a unique peroxidase containing extracellular matrix motifs and stabilizes collagen IV networks by forming sulfilimine crosslinks. PXDN gene knockout in Caenorhabditis elegans (C. elegans) and Drosophila results in the demise at the embryonic and larval stages. PXDN mutations le...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Kyung, Ham, Kyung A, Lee, Seung-Woo, Choi, Hong Seok, Kim, Hong-Sug, Kim, Hong Kyung, Shin, Hae-Sol, Seo, Kyoung Yul, Cho, Yejin, Nam, Ki Taek, Kim, In-Beom, Joe, Young Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941041/
https://www.ncbi.nlm.nih.gov/pubmed/31817535
http://dx.doi.org/10.3390/ijms20246144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941041/
https://www.ncbi.nlm.nih.gov/pubmed/31817535
http://dx.doi.org/10.3390/ijms20246144

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