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4-methylumbelliferone Prevents Liver Fibrosis by Affecting Hyaluronan Deposition, FSTL1 Expression and Cell Localization

4-methylumbelliferone (4MU) is an inhibitor of hyaluronan deposition and an active substance of hymecromone, a choleretic and antispasmodic drug. 4MU reported to be anti-fibrotic in mouse models; however, precise mechanism of action still requires further investigation. Here we describe the cellular...

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Detalles Bibliográficos
Autores principales: Andreichenko, Irina N., Tsitrina, Alexandra A., Fokin, Alexander V., Gabdulkhakova, Adelya I., Maltsev, Dmitry I., Perelman, Grigorii S., Bulgakova, Elena V., Kulikov, Alexey M., Mikaelyan, Arsen S., Kotelevtsev, Yuri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941058/
https://www.ncbi.nlm.nih.gov/pubmed/31847129
http://dx.doi.org/10.3390/ijms20246301