Cargando…

Sphingosine-1-Phosphate Enhances α(1)-Adrenergic Vasoconstriction via S1P2–G(12/13)–ROCK Mediated Signaling

Sphingosine-1-phosphate (S1P) has been implicated recently in the physiology and pathology of the cardiovascular system including regulation of vascular tone. Pilot experiments showed that the vasoconstrictor effect of S1P was enhanced markedly in the presence of phenylephrine (PE). Based on this ob...

Descripción completa

Detalles Bibliográficos
Autores principales: Panta, Cecília R., Ruisanchez, Éva, Móré, Dorottya, Dancs, Péter T., Balogh, Andrea, Fülöp, Ágnes, Kerék, Margit, Proia, Richard L., Offermanns, Stefan, Tigyi, Gábor J., Benyó, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941080/
https://www.ncbi.nlm.nih.gov/pubmed/31861195
http://dx.doi.org/10.3390/ijms20246361