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Sphingosine-1-Phosphate Enhances α(1)-Adrenergic Vasoconstriction via S1P2–G(12/13)–ROCK Mediated Signaling
Sphingosine-1-phosphate (S1P) has been implicated recently in the physiology and pathology of the cardiovascular system including regulation of vascular tone. Pilot experiments showed that the vasoconstrictor effect of S1P was enhanced markedly in the presence of phenylephrine (PE). Based on this ob...
Autores principales: | Panta, Cecília R., Ruisanchez, Éva, Móré, Dorottya, Dancs, Péter T., Balogh, Andrea, Fülöp, Ágnes, Kerék, Margit, Proia, Richard L., Offermanns, Stefan, Tigyi, Gábor J., Benyó, Zoltán |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941080/ https://www.ncbi.nlm.nih.gov/pubmed/31861195 http://dx.doi.org/10.3390/ijms20246361 |
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