Resveratrol Treatment Enhances the Cellular Response to Leptin by Increasing OBRb Content in Palmitate-Induced Steatotic HepG2 Cells

The interaction of leptin with its hepatic longest receptor (OBRb) promotes the phosphorylation of signal transducer and activator of transcription-3 (STAT3), protecting the liver from lipid accumulation. However, leptin signalling is disrupted in hepatic steatosis, causing leptin resistance. One pr...

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Detalles Bibliográficos
Autores principales: Ardid-Ruiz, Andrea, Ibars, Maria, Mena, Pedro, Del Rio, Daniele, Muguerza, Begoña, Arola, Lluís, Aragonès, Gerard, Suárez, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941089/
https://www.ncbi.nlm.nih.gov/pubmed/31842467
http://dx.doi.org/10.3390/ijms20246282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941089/
https://www.ncbi.nlm.nih.gov/pubmed/31842467
http://dx.doi.org/10.3390/ijms20246282

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