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Intra- and Inter-Tumor BRAF Heterogeneity in Acral Melanoma: An Immunohistochemical Analysis

The current development of BRAF inhibitors has revolutionized the treatment of unresectable melanoma. As the potential heterogeneity of BRAF mutations in melanoma has been reported, accurate detection of BRAF mutations are important. However, the genetic heterogeneity of acral melanoma—a distinct ty...

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Detalles Bibliográficos
Autores principales: Ito, Takamichi, Kaku-Ito, Yumiko, Murata, Maho, Ichiki, Toshio, Kuma, Yuki, Tanaka, Yuka, Ide, Taketoshi, Ohno, Fumitaka, Wada-Ohno, Maiko, Yamada, Yuichi, Oda, Yoshinao, Furue, Masutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941107/
https://www.ncbi.nlm.nih.gov/pubmed/31817947
http://dx.doi.org/10.3390/ijms20246191