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The Emerging Landscape of p53 Isoforms in Physiology, Cancer and Degenerative Diseases
p53, first described four decades ago, is now established as a master regulator of cellular stress response, the “guardian of the genome”. p53 contributes to biological robustness by behaving in a cellular-context dependent manner, influenced by several factors (e.g., cell type, active signalling pa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941119/ https://www.ncbi.nlm.nih.gov/pubmed/31835844 http://dx.doi.org/10.3390/ijms20246257 |