Newly Developed CK1-Specific Inhibitors Show Specifically Stronger Effects on CK1 Mutants and Colon Cancer Cell Lines

Protein kinases of the CK1 family can be involved in numerous physiological and pathophysiological processes. Dysregulated expression and/or activity as well as mutation of CK1 isoforms have previously been linked to tumorigenesis. Among all neoplastic diseases, colon and rectal cancer (CRC) represe...

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Detalles Bibliográficos
Autores principales: Liu, Congxing, Witt, Lydia, Ianes, Chiara, Bischof, Joachim, Bammert, Marie-Thérèse, Baier, Joana, Kirschner, Stefan, Henne-Bruns, Doris, Xu, Pengfei, Kornmann, Marko, Peifer, Christian, Knippschild, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941124/
https://www.ncbi.nlm.nih.gov/pubmed/31817920
http://dx.doi.org/10.3390/ijms20246184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941124/
https://www.ncbi.nlm.nih.gov/pubmed/31817920
http://dx.doi.org/10.3390/ijms20246184

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