Teleost IgD(+)IgM(−) B Cells Mount Clonally Expanded and Mildly Mutated Intestinal IgD Responses in the Absence of Lymphoid Follicles

Immunoglobulin D (IgD) is an ancient antibody with dual membrane-bound and fluid-phase antigen receptor functions. The biology of secreted IgD remains elusive. Here, we demonstrate that teleost IgD(+)IgM(−) plasmablasts constitute a major lymphocyte population in some mucosal surfaces, including the...

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Detalles Bibliográficos
Autores principales: Perdiguero, Pedro, Martín-Martín, Alba, Benedicenti, Ottavia, Díaz-Rosales, Patricia, Morel, Esther, Muñoz-Atienza, Estefanía, García-Flores, Mónica, Simón, Rocío, Soleto, Irene, Cerutti, Andrea, Tafalla, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941218/
https://www.ncbi.nlm.nih.gov/pubmed/31875534
http://dx.doi.org/10.1016/j.celrep.2019.11.101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941218/
https://www.ncbi.nlm.nih.gov/pubmed/31875534
http://dx.doi.org/10.1016/j.celrep.2019.11.101

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