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MiR-199a-modified exosomes from adipose tissue-derived mesenchymal stem cells improve hepatocellular carcinoma chemosensitivity through mTOR pathway

BACKGROUND: MiR-199a-3p (miR-199a) can enhance the chemosensitivity of hepatocellular carcinoma (HCC). Because of the easy degradation of miRNA by direct infusion, effective vehicle-mediated delivery of miR-199a may represent a new strategy for improving HCC chemotherapy. Considering mesenchymal ste...

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Detalles Bibliográficos
Autores principales: Lou, Guohua, Chen, Liang, Xia, Caixia, Wang, Weina, Qi, Jinjin, Li, Aichun, Zhao, Liying, Chen, Zhi, Zheng, Min, Liu, Yanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941283/
https://www.ncbi.nlm.nih.gov/pubmed/31898515
http://dx.doi.org/10.1186/s13046-019-1512-5