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Conserved genomic neighborhood is a strong but no perfect indicator for a direct interaction of microbial gene products

BACKGROUND: The order of genes in bacterial genomes is not random; for example, the products of genes belonging to an operon work together in the same pathway. The cotranslational assembly of protein complexes is deemed to conserve genomic neighborhoods even stronger than a common function. This is...

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Detalles Bibliográficos
Autores principales: Esch, Robert, Merkl, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941341/
https://www.ncbi.nlm.nih.gov/pubmed/31900122
http://dx.doi.org/10.1186/s12859-019-3200-z