Loss of Stag2 cooperates with EWS-FLI1 to transform murine Mesenchymal stem cells

BACKGROUND: Ewing sarcoma is a malignancy of primitive cells, possibly of mesenchymal origin. It is probable that genetic perturbations other than EWS-FLI1 cooperate with it to produce the tumor. Sequencing studies identified STAG2 mutations in approximately 15% of cases in humans. In the present st...

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Detalles Bibliográficos
Autores principales: El Beaino, Marc, Liu, Jiayong, Wasylishen, Amanda R., Pourebrahim, Rasoul, Migut, Agata, Bessellieu, Bryan J., Huang, Ke, Lin, Patrick P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941350/
https://www.ncbi.nlm.nih.gov/pubmed/31898537
http://dx.doi.org/10.1186/s12885-019-6465-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941350/
https://www.ncbi.nlm.nih.gov/pubmed/31898537
http://dx.doi.org/10.1186/s12885-019-6465-8

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