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Loss of Stag2 cooperates with EWS-FLI1 to transform murine Mesenchymal stem cells
BACKGROUND: Ewing sarcoma is a malignancy of primitive cells, possibly of mesenchymal origin. It is probable that genetic perturbations other than EWS-FLI1 cooperate with it to produce the tumor. Sequencing studies identified STAG2 mutations in approximately 15% of cases in humans. In the present st...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941350/ https://www.ncbi.nlm.nih.gov/pubmed/31898537 http://dx.doi.org/10.1186/s12885-019-6465-8 |