An in vitro toolbox to accelerate anti-malarial drug discovery and development

BACKGROUND: Modelling and simulation are being increasingly utilized to support the discovery and development of new anti-malarial drugs. These approaches require reliable in vitro data for physicochemical properties, permeability, binding, intrinsic clearance and cytochrome P450 inhibition. This wo...

Descripción completa

Detalles Bibliográficos
Autores principales: Charman, Susan A., Andreu, Alice, Barker, Helena, Blundell, Scott, Campbell, Anna, Campbell, Michael, Chen, Gong, Chiu, Francis C. K., Crighton, Elly, Katneni, Kasiram, Morizzi, Julia, Patil, Rahul, Pham, Thao, Ryan, Eileen, Saunders, Jessica, Shackleford, David M., White, Karen L., Almond, Lisa, Dickins, Maurice, Smith, Dennis A., Moehrle, Joerg J., Burrows, Jeremy N., Abla, Nada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941357/
https://www.ncbi.nlm.nih.gov/pubmed/31898492
http://dx.doi.org/10.1186/s12936-019-3075-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941357/
https://www.ncbi.nlm.nih.gov/pubmed/31898492
http://dx.doi.org/10.1186/s12936-019-3075-5

Ejemplares similares