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Bayesian mixture regression analysis for regulation of Pluripotency in ES cells
BACKGROUND: Observed levels of gene expression strongly depend on both activity of DNA binding transcription factors (TFs) and chromatin state through different histone modifications (HMs). In order to recover the functional relationship between local chromatin state, TF binding and observed levels...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941360/ https://www.ncbi.nlm.nih.gov/pubmed/31898480 http://dx.doi.org/10.1186/s12859-019-3331-2 |