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Bayesian mixture regression analysis for regulation of Pluripotency in ES cells

BACKGROUND: Observed levels of gene expression strongly depend on both activity of DNA binding transcription factors (TFs) and chromatin state through different histone modifications (HMs). In order to recover the functional relationship between local chromatin state, TF binding and observed levels...

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Detalles Bibliográficos
Autores principales: Aflakparast, Mehran, Geeven, Geert, de Gunst, Mathisca C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941360/
https://www.ncbi.nlm.nih.gov/pubmed/31898480
http://dx.doi.org/10.1186/s12859-019-3331-2