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TP53 and PTEN mutations were shared in concurrent germ cell tumor and acute megakaryoblastic leukemia
BACKGROUND: The occurrence of a mediastinal germ cell tumor (GCT) and hematological malignancy in the same patient is very rare. Due to its rarity, there have been only two reports of the concurrent cases undergoing detailed genetic analysis with whole-exome sequencing (WES), and the possible clonal...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941398/ https://www.ncbi.nlm.nih.gov/pubmed/31898539 http://dx.doi.org/10.1186/s12885-019-6497-0 |