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TP53 and PTEN mutations were shared in concurrent germ cell tumor and acute megakaryoblastic leukemia

BACKGROUND: The occurrence of a mediastinal germ cell tumor (GCT) and hematological malignancy in the same patient is very rare. Due to its rarity, there have been only two reports of the concurrent cases undergoing detailed genetic analysis with whole-exome sequencing (WES), and the possible clonal...

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Detalles Bibliográficos
Autores principales: Akizuki, Keiichi, Sekine, Masaaki, Kogure, Yasunori, Kameda, Takuro, Shide, Kotaro, Koya, Junji, Kamiunten, Ayako, Kubuki, Yoko, Tahira, Yuki, Hidaka, Tomonori, Kiwaki, Takumi, Tanaka, Hiroyuki, Sato, Yuichiro, Kataoka, Hiroaki, Kataoka, Keisuke, Shimoda, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941398/
https://www.ncbi.nlm.nih.gov/pubmed/31898539
http://dx.doi.org/10.1186/s12885-019-6497-0