Dysregulation of RNA Splicing in Tauopathies

Pathological aggregation of RNA binding proteins (RBPs) is associated with dysregulation of RNA splicing in PS19 P301S tau transgenic mice and in Alzheimer’s disease brain tissues. The dysregulated splicing particularly affects genes involved in synaptic transmission. The effects of neuroprotective...

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Detalles Bibliográficos
Autores principales: Apicco, Daniel J., Zhang, Cheng, Maziuk, Brandon, Jiang, Lulu, Ballance, Heather I., Boudeau, Samantha, Ung, Choong, Li, Hu, Wolozin, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941411/
https://www.ncbi.nlm.nih.gov/pubmed/31875547
http://dx.doi.org/10.1016/j.celrep.2019.11.093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941411/
https://www.ncbi.nlm.nih.gov/pubmed/31875547
http://dx.doi.org/10.1016/j.celrep.2019.11.093

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