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Activation of phagocytosis by immune checkpoint blockade

Inhibition of macrophage-mediated phagocytosis has emerged as an essential mechanism for tumor immune evasion. One mechanism inhibiting the innate response is the presence of the macrophage inhibitory molecule, signal regulatory protein-α (SIRPα), on tumor-associated macrophages (TAMs) and its cogna...

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Detalles Bibliográficos
Autores principales: Li, Chia-Wei, Lai, Yun-Ju, Hsu, Jennifer L., Hung, Mien-Chie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941417/
https://www.ncbi.nlm.nih.gov/pubmed/30062558
http://dx.doi.org/10.1007/s11684-018-0657-5