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The role of mutations at codons 32, 47, 54, and 90 in HIV-1 protease flap dynamics
Treatment of Human Immunodeficiency Virus remains challenging due to the emergence of drug resistant strains under the selective pressure produced by standard anti-retroviral therapy. To explore the structural mechanisms of drug resistance, we performed 40 ns molecular dynamics simulations on three...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Applied Systems srl
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941557/ https://www.ncbi.nlm.nih.gov/pubmed/32309558 http://dx.doi.org/10.15190/d.2014.19 |