Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria

Plant-derived lignans, consumed daily by most individuals, are thought to protect against cancer and other diseases(1); however, their bioactivity requires gut bacterial conversion to enterolignans(2). Here, we dissect a four-species bacterial consortium sufficient for all five reactions in this pat...

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Detalles Bibliográficos
Autores principales: Bess, Elizabeth N., Bisanz, Jordan E., Yarza, Fauna, Bustion, Annamarie, Rich, Barry E., Li, Xingnan, Kitamura, Seiya, Waligurski, Emily, Ang, Qi Yan, Alba, Diana L., Spanogiannopoulos, Peter, Nayfach, Stephen, Koliwad, Suneil K., Wolan, Dennis W., Franke, Adrian A., Turnbaugh, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941677/
https://www.ncbi.nlm.nih.gov/pubmed/31686027
http://dx.doi.org/10.1038/s41564-019-0596-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941677/
https://www.ncbi.nlm.nih.gov/pubmed/31686027
http://dx.doi.org/10.1038/s41564-019-0596-1

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