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Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria
Plant-derived lignans, consumed daily by most individuals, are thought to protect against cancer and other diseases(1); however, their bioactivity requires gut bacterial conversion to enterolignans(2). Here, we dissect a four-species bacterial consortium sufficient for all five reactions in this pat...
Autores principales: | Bess, Elizabeth N., Bisanz, Jordan E., Yarza, Fauna, Bustion, Annamarie, Rich, Barry E., Li, Xingnan, Kitamura, Seiya, Waligurski, Emily, Ang, Qi Yan, Alba, Diana L., Spanogiannopoulos, Peter, Nayfach, Stephen, Koliwad, Suneil K., Wolan, Dennis W., Franke, Adrian A., Turnbaugh, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941677/ https://www.ncbi.nlm.nih.gov/pubmed/31686027 http://dx.doi.org/10.1038/s41564-019-0596-1 |
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