Cargando…

LIR motifs and the membrane-targeting domain are complementary in the function of RavZ

The bacterial effector protein RavZ is secreted by the intracellular pathogen Legionella pneumophila and inhibits host autophagy through an irreversible deconjugation of mammalian ATG8 (mATG8) proteins from autophagosome membranes. However, the roles of the LC3 interacting region (LIR) motifs in Rav...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Sang-Won, Jun, Yong-Woo, Jeon, Pureum, Lee, You-Kyung, Park, Ju-Hui, Lee, Seung-Hwan, Lee, Jin-A, Jang, Deok-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941762/ https://www.ncbi.nlm.nih.gov/pubmed/31722778 http://dx.doi.org/10.5483/BMBRep.2019.52.12.211

Ejemplares similares

Monitoring LC3- or GABARAP-positive autophagic membranes using modified RavZ-based probes
por: Park, Sang-Won, et al.
Publicado: (2019)

Deciphering the role of a membrane-targeting domain in assisting endosomal and autophagic membrane localization of a RavZ protein catalytic domain
por: Park, Jui-Hee, et al.
Publicado: (2021)

Development of GABARAP family protein-sensitive LIR-based probes for neuronal autophagy
por: Jeon, Pureum, et al.
Publicado: (2019)

Legionella RavZ Plays a Role in Preventing Ubiquitin Recruitment to Bacteria-Containing Vacuoles
por: Kubori, Tomoko, et al.
Publicado: (2017)

Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins
por: Yang, Aimin, et al.
Publicado: (2017)

Distinct Mechanisms for Processing Autophagy Protein LC3‐PE by RavZ and ATG4B
por: Yang, Aimin, et al.
Publicado: (2020)

Legionella longbeachae effector protein RavZ inhibits autophagy and regulates phagosome ubiquitination during infection
por: Shi, Yunjia, et al.
Publicado: (2023)

iLIR database: A web resource for LIR motif-containing proteins in eukaryotes
por: Jacomin, Anne-Claire, et al.
Publicado: (2016)

iLIR@viral: A web resource for LIR motif-containing proteins in viruses
por: Jacomin, Anne-Claire, et al.
Publicado: (2017)

Tir & lir /
por: Redonnet, Marie
Publicado: (1988)

LIR Motif-Containing Hyperdisulfide β-Ginkgotide is Cytoprotective, Adaptogenic, and Scaffold-Ready
por: Dutta, Bamaprasad, et al.
Publicado: (2019)

Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
por: Wirth, Martina, et al.
Publicado: (2021)

LIRcentral: a manually curated online database of experimentally validated functional LIR motifs
por: Chatzichristofi, Agathangelos, et al.
Publicado: (2023)

Corrigendum to Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity
por: Wirth, Martina, et al.
Publicado: (2021)

The RAV1 transcription factor positively regulates leaf senescence in Arabidopsis
por: Woo, Hye Ryun, et al.
Publicado: (2010)

Cyclic-di-GMP binds to histidine kinase RavS to control RavS-RavR phosphotransfer and regulates the bacterial lifestyle transition between virulence and swimming
por: Cheng, Shou-Ting, et al.
Publicado: (2019)

SNAREing an ARP requires a LIR
por: Tooze, Sharon A.
Publicado: (2018)

A Conserved LIR Motif in Connexins Mediates Ubiquitin-Independent Binding to LC3/GABARAP Proteins
por: Catarino, Steve, et al.
Publicado: (2020)

Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs
por: Birgisdottir, Åsa Birna, et al.
Publicado: (2019)

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy
por: von Muhlinen, Natalia, et al.
Publicado: (2012)

Genome-Wide Analysis of RAV Transcription Factors and Functional Characterization of Anthocyanin-Biosynthesis-Related RAV Genes in Pear
por: Liu, Jianlong, et al.
Publicado: (2021)

Genome-Wide Analysis of the RAV Gene Family in Wheat and Functional Identification of TaRAV1 in Salt Stress
por: Luo, Yun-Xin, et al.
Publicado: (2022)

Nonmuscle myosin IIB regulates Parkin-mediated mitophagy associated with amyotrophic lateral sclerosis-linked TDP-43
por: Jun, Mi-Hee, et al.
Publicado: (2020)

Comprehensive analysis of cucumber RAV family genes and functional characterization of CsRAV1 in salt and ABA tolerance in cucumber
por: Li, Jialin, et al.
Publicado: (2023)

Genome-Wide Analysis of the RAV Family in Soybean and Functional Identification of GmRAV-03 Involvement in Salt and Drought Stresses and Exogenous ABA Treatment
por: Zhao, Shu-Ping, et al.
Publicado: (2017)

The Activation and Selectivity of the Legionella RavD Deubiquitinase
por: Schulze-Niemand, Eric, et al.
Publicado: (2021)

Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex
por: Jessop, Matthew, et al.
Publicado: (2020)

Loneliness in Intimate Relationships Scale (LIRS): Development and Validation
por: Rokach, Ami, et al.
Publicado: (2022)

Development of new tools to study membrane-anchored mammalian Atg8 proteins
por: Park, Sang-Won, et al.
Publicado: (2022)

Dr. Jekyll and Mr. Hyde? Physiology and Pathology of Neuronal Stress Granules
por: Jeon, Pureum, et al.
Publicado: (2021)

Regulation of Cellular Ribonucleoprotein Granules: From Assembly to Degradation via Post-translational Modification
por: Jeon, Pureum, et al.
Publicado: (2022)

The MdWRKY31 transcription factor binds to the MdRAV1 promoter to mediate ABA sensitivity
por: Zhao, Xian-Yan, et al.
Publicado: (2019)

RAVS Study: One Indian Single Center Analysis of Patients with VTE
por: Basavanthappa, Rajendra Prasad, et al.
Publicado: (2019)

The control of endopolygalacturonase expression by the sugarcane RAV transcription factor during aerenchyma formation
por: Tavares, Eveline Q P, et al.
Publicado: (2019)

iLIR: A web resource for prediction of Atg8-family interacting proteins
por: Kalvari, Ioanna, et al.
Publicado: (2014)

LIR and APEAR, two distinct Atg8-binding features within Atg4
por: Kriegenburg, Franziska, et al.
Publicado: (2017)

LIR-1 and PDTF-1 regulate the permeability barrier function of the C. elegans cuticle
por: Sandhu, Anjali, et al.
Publicado: (2021)

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1
por: Zhou, Jianwen, et al.
Publicado: (2022)

Extracellular nucleoprotein exacerbates influenza virus pathogenesis by activating Toll-like receptor 4 and the NLRP3 inflammasome
por: Kim, Chang-Ung, et al.
Publicado: (2022)

Crystal structure of LIR-2 (ILT4) at 1.8 Å: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18
por: Willcox, Benjamin E, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_cv2l7pvlacfbfsf2mhii0egil3