Sequencing artifacts derived from a library preparation method using enzymatic fragmentation

DNA fragmentation is a fundamental step during library preparation in hybridization capture-based, short-read sequencing. Ultra-sonication has been used thus far to prepare DNA of an appropriate size, but this method is associated with a considerable loss of DNA sample. More recently, studies have e...

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Detalles Bibliográficos
Autores principales: Tanaka, Norio, Takahara, Akihisa, Hagio, Taichi, Nishiko, Rika, Kanayama, Junko, Gotoh, Osamu, Mori, Seiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941819/
https://www.ncbi.nlm.nih.gov/pubmed/31899787
http://dx.doi.org/10.1371/journal.pone.0227427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941819/
https://www.ncbi.nlm.nih.gov/pubmed/31899787
http://dx.doi.org/10.1371/journal.pone.0227427

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