Cargando…

White Spot Syndrome Virus Establishes a Novel IE1/JNK/c-Jun Positive Feedback Loop to Drive Replication

Viruses need to hijack and manipulate host proteins to guarantee their replication. Herein, we uncovered that the DNA virus white spot syndrome virus (WSSV) established a novel positive feedback loop by hijacking the host JNK pathway via its immediate-early 1 (IE1) protein to drive replication. Spec...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Sheng, Li, Haoyang, Weng, Shaoping, Li, Chaozheng, He, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941876/
https://www.ncbi.nlm.nih.gov/pubmed/31884168
http://dx.doi.org/10.1016/j.isci.2019.100752