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White Spot Syndrome Virus Establishes a Novel IE1/JNK/c-Jun Positive Feedback Loop to Drive Replication
Viruses need to hijack and manipulate host proteins to guarantee their replication. Herein, we uncovered that the DNA virus white spot syndrome virus (WSSV) established a novel positive feedback loop by hijacking the host JNK pathway via its immediate-early 1 (IE1) protein to drive replication. Spec...
Autores principales: | Wang, Sheng, Li, Haoyang, Weng, Shaoping, Li, Chaozheng, He, Jianguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941876/ https://www.ncbi.nlm.nih.gov/pubmed/31884168 http://dx.doi.org/10.1016/j.isci.2019.100752 |
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