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Sharpening the Molecular Scissors: Advances in Gene-Editing Technology
The ability to precisely modify human genes has been made possible by the development of tools such as meganucleases, zinc finger nucleases, TALENs, and CRISPR/Cas. These now make it possible to generate targeted deletions, insertions, gene knock outs, and point variants; to modulate gene expression...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941877/ https://www.ncbi.nlm.nih.gov/pubmed/31901636 http://dx.doi.org/10.1016/j.isci.2019.100789 |