Cargando…
Heparin-mediated delivery of bone morphogenetic protein-2 improves spatial localization of bone regeneration
Supraphysiologic doses of bone morphogenetic protein-2 (BMP-2) are used clinically to promote bone formation in fracture nonunions, large bone defects, and spinal fusion. However, abnormal bone formation (i.e., heterotopic ossification) caused by rapid BMP-2 release from conventional collagen sponge...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941907/ https://www.ncbi.nlm.nih.gov/pubmed/31922007 http://dx.doi.org/10.1126/sciadv.aay1240 |